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Toxicological information

Dermal absorption

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Administrative data

Endpoint:
dermal absorption
Type of information:
read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
weight of evidence
Justification for type of information:
Reference to CSR in section 13.1 for read-across justification
Cross-reference
Reason / purpose for cross-reference:
read-across source
Reference
Endpoint:
dermal absorption
Type of information:
other: Scientific review from a German authority determining maximum workplace concentrations with reference to original data
Adequacy of study:
weight of evidence
Study period:
1990
Reliability:
3 (not reliable)
Rationale for reliability incl. deficiencies:
other: Scientific review from a German authority determining maximum workplace concentrations with reference to original data; info on absorption of 1-pentyl acetate through skin; conclusions based on calculation and no official test guideline
Principles of method if other than guideline:
estimation of dermal absorption

Data source

Materials and methods

Principles of method if other than guideline:
estimation of dermal absorption

Test material

Constituent 1
Chemical structure
Reference substance name:
Isopentyl acetate
EC Number:
204-662-3
EC Name:
Isopentyl acetate
Cas Number:
123-92-2
Molecular formula:
C7H14O2
IUPAC Name:
3-methylbutan-1-ol

Results and discussion

Applicant's summary and conclusion