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Physical & Chemical properties

Solubility in organic solvents / fat solubility

Administrative data

Endpoint:
solubility in organic solvents / fat solubility
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Test procedure in accordance with generally accepted scientific standards and described in sufficient detail; however, non-GLP

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2003
Report Date:
2003

Materials and methods

Test guideline
Qualifier:
no guideline available
Deviations:
not applicable
GLP compliance:
no

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
not specified

Results and discussion

Test substance stable:
ambiguous

Any other information on results incl. tables

Stability

The test substance is stable against aprotic solvents, but can react with protic solvents under addition to carbamic acid derivates. With alcohols this reaction takes place noticeably first above the melting point of about 50°C.

Solubility

 Solvent  Solubility [%]  Temperature [°C]
 Acetone  >50  ~20
 Light Benzin  >50  ~20
 Toluene  >60  ~20
 Ethylacetate  >50  ~20
 Tetrahydrofurane  >50  ~20
 Dimehtylformamide  ~24  ~20
 Soybean Oil  ~22  ~25
 Isopropanol  ~12.6  ~20
 Ethanol  ~4.8  ~20
 Polyethyleneglycol  <1  ~25
 Methanol  ~1.2  ~10
 Methanol  ~2.4  ~20
 Methanol  ~4.0  ~30
 Methanol  ~5.5  ~40
 Methanol  ~8.0  ~50
 Water  <0.1 ~20 

Applicant's summary and conclusion

Conclusions:
Solubility > 50% in acetone, light benzin, toluene, ethyl acetate and tetrahydrofurane (at 20-25°C)
Solubility between 10 and 25% in dimethylformamide, soybean oil and isopropanol (at 20-25°C)
Solubility < 5% in ethanol, polyethylene glycol and methanol (at 20-25°C)