Registration Dossier
Registration Dossier
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EC number: 203-696-6 | CAS number: 109-69-3
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: only short abstract; insufficient for assessment to few data available
Data source
Reference
- Reference Type:
- publication
- Title:
- Hygienische Begründung für den zulässigen Gehalt Benzylchlorids und Butylchlorids in den Gewässern
- Author:
- Rudnev, M.I. Rudnev, M.I.; Tomasevskaja, L.A.; Vinogradov, G.I.; Kapustin, A.A.; Zoldakova, Z.I.; Leonskaja, G.I.
- Year:
- 1 979
- Bibliographic source:
- Gig. Sanit 3, 11-15
Materials and methods
- Principles of method if other than guideline:
- LD50 determination
- GLP compliance:
- no
- Remarks:
- test conducted before the development of GLP
- Test type:
- other: no data
Test material
- Reference substance name:
- 1-chlorobutane
- EC Number:
- 203-696-6
- EC Name:
- 1-chlorobutane
- Cas Number:
- 109-69-3
- Molecular formula:
- C4H9Cl
- IUPAC Name:
- 1-chlorobutane
- Details on test material:
- - Name of test material (as cited in study report): Chlorbutyl
Constituent 1
Test animals
- Species:
- rat
- Strain:
- other: albino rats
- Sex:
- not specified
Administration / exposure
- Route of administration:
- oral: unspecified
- Vehicle:
- not specified
- Doses:
- no data
- No. of animals per sex per dose:
- no data
- Control animals:
- not specified
Results and discussion
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- 2 200 mg/kg bw
- Based on:
- test mat.
Applicant's summary and conclusion
- Interpretation of results:
- Category 5 based on GHS criteria
- Remarks:
- Migrated information
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