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Physical & Chemical properties

Water solubility

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Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
GLP compliance:
no
Remarks:
The tests were following as close as possible the GLP guidelines proposed by OECD
Type of method:
flask method
Water solubility:
0.4 µg/L
Temp.:
20.7 °C
pH:
5.91
Remarks on result:
other: Co(OH)O concentration at 0 hour sampling time at 1 mg/L loading. Sample analysis was conducted in triplicate per test vessel (3 test vessels per loading). Average value from the tests is given.
Water solubility:
4.8 µg/L
Temp.:
21.2 °C
pH:
6.05
Remarks on result:
other: Co(OH)O concentration at 24 hour sampling time at 1 mg/L loading. Sample analysis was conducted in triplicate per test vessel (3 test vessels per loading). Average value from the tests is given.
Water solubility:
6.4 µg/L
Temp.:
21.3 °C
pH:
6.04
Remarks on result:
other: Co(OH)O concentration at 48 hour sampling time at 1 mg/L loading. Sample analysis was conducted in triplicate per test vessel (3 test vessels per loading). Average value from the tests is given.
Water solubility:
8.2 µg/L
Temp.:
21.4 °C
pH:
6.03
Remarks on result:
other: Co(OH)O concentration at 96 hour sampling time at 1 mg/L loading. Sample analysis was conducted in triplicate per test vessel (3 test vessels per loading). Average value from the tests is given.
Water solubility:
11.6 µg/L
Temp.:
21.2 °C
pH:
5.96
Remarks on result:
other: Co(OH)O concentration at 168 hour sampling time at 1 mg/L loading. Sample analysis was conducted in triplicate per test vessel (3 test vessels per loading). Average value from the tests is given.
Water solubility:
30.7 µg/L
Temp.:
22.6 °C
pH:
6.06
Remarks on result:
other: Co(OH)O concentration at 672 hour sampling time at 1 mg/L loading. Sample analysis was conducted in triplicate per test vessel (3 test vessels per loading). Average value from the tests is given.
Water solubility:
2.1 µg/L
Temp.:
21.7 °C
pH:
5.9
Remarks on result:
other: Co(OH)O concentration at 0 hour sampling time at 10 mg/L loading. Sample analysis was conducted in triplicate per test vessel (3 test vessels per loading). Average value from the tests is given.
Water solubility:
48.7 µg/L
Temp.:
23 °C
pH:
6.02
Remarks on result:
other: Co(OH)O concentration at 24 hour sampling time at 10 mg/L loading. Sample analysis was conducted in triplicate per test vessel (3 test vessels per loading). Average value from the tests is given.
Water solubility:
68.7 µg/L
Temp.:
22.1 °C
pH:
6.03
Remarks on result:
other: Co(OH)O concentration at 48 hour sampling time at 10 mg/L loading. Sample analysis was conducted in triplicate per test vessel (3 test vessels per loading). Average value from the tests is given.
Water solubility:
88.2 µg/L
Temp.:
21.9 °C
pH:
6.21
Remarks on result:
other: Co(OH)O concentration at 96 hour sampling time at 10 mg/L loading. Sample analysis was conducted in triplicate per test vessel (3 test vessels per loading). Average value from the tests is given.
Conclusions:
Under the conditions of the transformation/dissolution test, the dissolution of Co(OH)O is 30.7 µg/L at 1 mg/L loading for the 28-day endpoint.
The dissolution of Co(OH)O is 105.4 µg/L at 10 mg/L loading for the 7-day endpoint.
The dissolution of Co(OH)O is 858.5 µg/L at 100 mg/L loading for the 7-day endpoint.
Executive summary:
A seven day transformation/dissolution test according to the OECD guideline 29 and the GHS (Annex 10) protocol was run on Co(OH)O at a mass loading of 10 and 100 mg/L, at a pH of 6.0 Also a 28 day transformation/dissolution was run on Co(OH)O at a mass loading of 1 mg/L and at a pH of 6.0. Under the conditions of this test, the dissolution of Co(OH)O is 30.7 µg/L for the 28 -day endpoint (1 mg/L loading), 105.4 µg/L for the 7 -day endpoint (10 mg/L loading) and 858.5 µg/L for the 7 -day endpoint (100 mg/L loading).
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
GLP compliance:
no
Remarks:
The tests were following as close as possible the GLP guidelines proposed by OECD
Type of method:
flask method
Water solubility:
105.4 µg/L
Temp.:
22.1 °C
pH:
6.06
Remarks on result:
other: Co(OH)O concentration at 168 hour sampling time at 10 mg/L loading. Sample analysis was conducted in triplicate per test vessel (3 test vessels per loading). Average value from the tests is given.
Water solubility:
11.6 µg/L
Temp.:
21.5 °C
pH:
5.85
Remarks on result:
other: Co(OH)O concentration at 0 hour sampling time at 100 mg/L loading. Sample analysis was conducted in triplicate per test vessel (3 test vessels per loading). Average value from the tests is given.
Water solubility:
392.2 µg/L
Temp.:
21.4 °C
pH:
6.21
Remarks on result:
other: Co(OH)O concentration at 24 hour sampling time at 100 mg/L loading. Sample analysis was conducted in triplicate per test vessel (3 test vessels per loading). Average value from the tests is given.
Water solubility:
514.7 µg/L
Temp.:
20.4 °C
pH:
5.98
Remarks on result:
other: Co(OH)O concentration at 48 hour sampling time at 100 mg/L loading. Sample analysis was conducted in triplicate per test vessel (3 test vessels per loading). Average value from the tests is given.
Water solubility:
651.6 µg/L
Temp.:
21.9 °C
pH:
6.21
Remarks on result:
other: Co(OH)O concentration at 96 hour sampling time at 100 mg/L loading. Sample analysis was conducted in triplicate per test vessel (3 test vessels per loading). Average value from the tests is given.
Water solubility:
858.5 µg/L
Temp.:
20.7 °C
pH:
6.04
Remarks on result:
other: Co(OH)O concentration at 168 hour sampling time at 100 mg/L loading. Sample analysis was conducted in triplicate per test vessel (3 test vessels per loading). Average value from the tests is given.
Conclusions:
Under the conditions of the transformation/dissolution test, the dissolution of Co(OH)O is 30.7 µg/L at 1 mg/L loading for the 28-day endpoint.
The dissolution of Co(OH)O is 105.4 µg/L at 10 mg/L loading for the 7-day endpoint.
The dissolution of Co(OH)O is 858.5 µg/L at 100 mg/L loading for the 7-day endpoint.
Executive summary:
A seven day transformation/dissolution test according to the OECD guideline 29 and the GHS (Annex 10) protocol was run on Co(OH)O at a mass loading of 10 and 100 mg/L, at a pH of 6.0 Also a 28 day transformation/dissolution was run on Co(OH)O at a mass loading of 1 mg/L and at a pH of 6.0. Under the conditions of this test, the dissolution of Co(OH)O is 30.7 µg/L for the 28 -day endpoint (1 mg/L loading), 105.4 µg/L for the 7 -day endpoint (10 mg/L loading) and 858.5 µg/L for the 7 -day endpoint (100 mg/L loading).
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2006-09-19 to 2006-12-04
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Remarks:
The stability of the test substance is missing.
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
Version / remarks:
, 1995
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.6 (Water Solubility)
Version / remarks:
, 1992
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Remarks:
signed 2005-11
Type of method:
column elution method
Water solubility:
1 084 µg/L
Conc. based on:
element
Incubation duration:
ca. 95 h
Temp.:
20 °C
pH:
>= 7.22 - <= 7.71
Remarks on result:
other: loading: 128.8 mg of the test item was mixed with 6.35 g of glass beads
Water solubility:
55 µg/L
Conc. based on:
element
Incubation duration:
ca. 95 h
Temp.:
37 °C
pH:
>= 7.92 - <= 8.21
Remarks on result:
other: loading: 122.10 mg of test item was mixed with 6.22 g of glass beads
Details on results:
Total elution times were about 95 hours at 20°C and at 37°C. The measured results differ by less than 30%. Therefore, the study is considered to be valid.

The water solubility of Cobald oxyhydroxide was found to be

at 20 °C: 1084 µg/L (+/- 63 µg/L)

at 37 °C: 55 µg/L (+/-3.4 µg/L)

using the column elution method.

Conclusions:
Interpretation of results: slightly soluble (0.1-100 mg/L)
The water solubility of Cobalt oxyhydroxide was found to be at 20 °C 746 µg/L (+/-43 µg/L) and at 37 °C 38.1 µg/L (+/-2.3 µg/L) using the column elution method.

Description of key information

Cobalt hydroxide oxide has a water solubility of 746 µg/L (+/-43 µg/L) at 20 °C and 38.1 µg/L (+/-2.3 µg/L) at 37 °C.

Key value for chemical safety assessment

Water solubility:
746 µg/L
at the temperature of:
20 °C

Additional information