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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

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Diss Factsheets

Physical & Chemical properties

Dissociation constant

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Description of key information

Dissociation constant (EDTMP-xNa): EDTMP acid has eight ionisable phosphonate groups.  

Key value for chemical safety assessment

Additional information

The dissociation constant of EDTMP-xNa is read across from its parent acid. Eight dissociation constants as listed below were obtained for the acid using an appropriate estimation method. The result is considered reliable and selected as key study.

pKa1 = 1.3
pKa2 = 2.7
pKa3 = 4.2
pKa4 = 5.7
pKa5 = 5.9
pKa6 = 7.3

pKa7 = 8.8

pKa8 = >10

Also, in a secondary source to which no reliability could be assigned, EDTMP-H has eight dissociation constants as listed below:

1.46 
2.72 
5.05
6.18 
6.63

7.43 
9.22

10.60 


 

An approximate experimental determination, using stocichiometric titration and pH determination of aqueous solutions, has been conducted. This is considered to provide suitable and practical information, which is fit for purpose in the context of REACH chemical safety assessment. This data is reported in section 4.20.