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Vapour pressure

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Reference
Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
August 17, 2011 - January 10, 2012
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Deviations:
no
Qualifier:
according to
Guideline:
EU Method A.4 (Vapour Pressure)
Deviations:
no
GLP compliance:
yes (incl. certificate)
Type of method:
effusion method: by loss of weight or by trapping vaporisate
Key result
Temp.:
20 °C
Vapour pressure:
< 0.002 Pa
Key result
Temp.:
25 °C
Vapour pressure:
< 0.004 Pa

The weight loss of the test substance at 110°C, 120°C, 130°C and 140°C was lower than the weight loss of hexachlorobenzene at the same temperatures. The results of the vapour pressure for the test substance at 20°C and 25°C are:

 

20°C

25°C

 

[Pa]

[mm Hg]

[Pa]

[mm Hg]

Test substance

< 1.5 x 10-3

< 1.1 x 10-5

< 4.2 x 10-3

< 3.2 x 10-5

Conclusions:
The isothermal TGA effusion method was applied for the determination of the vapour pressure of the substance, in accordance with OECD 104, EU Method A.4 and GLP. The vapour pressure of the test substance at 20°C (293K) and 25°C (293K) was < 0.0015 Pa and < 0.0042 Pa, respectively

Description of key information

The vapour pressure of the substance was determined using the isothermal thermogravimetric effusion method in a GLP study according to EC A.4, OECD 104 and OPPTS 830.7950. The constants specific for the experimental arrangement were determined using a set of five reference substances. Since the substance contained a high percentage of water,the measurements were performed at temperatures > 100°C to allow the water to evaporate before measuring weight loss as a function of time. Weight losses of the substance were measured at 160°C, 170°C, 180°C and 190°C. The experiment was performed in duplicate. From all results, the vapour pressure regression curve (log PT as a function of 1/T; with T in K) of the substance was constructed. The vapour pressure of the solid, water-free part of the substance was calculated (extrapolated) from the vapour pressure curve to be 1.5E-7 Pa and 3.7E-7 Pa at 20°C and 25°C, resp.  

Key value for chemical safety assessment

Vapour pressure:
0 Pa
at the temperature of:
20 °C

Additional information

The vapour pressure of the solid, water-free part of the substance was determined to be 1.5E-7 Pa and 3.7E-7 Pa at 20°C and 25°C, resp.