Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Endpoint summary

Administrative data

Description of key information

Additional information

In a GLP guideline study according to OECD 301 C L-arginine showed to be readily biodegradable.

Most studies are waived in accordance with REACH.

  • In accordance with Annex IX sections 9.2.1.2 to 2 and section 9.2.1.4 columns 2 simulation tests on the biodegradation in surface water or sediment as well as soil are therefore not necessary.
  • Also, a study on hydrolysis does not need to be conducted in accordance with REACH Annex VIII No. 9.2.2.1 column 2, the study does not need to be conducted if the substance is readily biodegradable.
  • According to REACH Annex VIII section 9.3.1 column 2, a study for bioaccumulation does not need to be conducted if the substance has low potential for bioaccumulation (log Kow < 3) and/or the substance and its degradation products decompose rapidly. Both conditions apply for L-arginine. Therefore and for reasons of animals welfare a study is not deemed necessary.
  • In accordance with REACH Annex VIII section 9.3.1. column 2 as well as REACH Annex IX section 9.3.3. column 2 the study on adsorption/desorption screening (required in section 9.3.1. column 1) does not need to be conducted as the substance has a low log Kow as well as the substance and its degradation products decompose rapidly. Adsorption to solid soilphase is not expected. From the water surface L-arginine will not evaporate into the atmosphere.