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Long-term toxicity to aquatic invertebrates

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Reference
Endpoint:
long-term toxicity to aquatic invertebrates
Type of information:
experimental study
Adequacy of study:
key study
Study period:
February 2, 1990
Reliability:
2 (reliable with restrictions)
Qualifier:
according to guideline
Guideline:
other: ASTM E 729-80 Standard Practice for Conducting Acute Toxicity Tests with Fishes, Macroinvertebrates, and amphibians
GLP compliance:
not specified
Test organisms (species):
Ceriodaphnia dubia
Test type:
static
Water media type:
freshwater
Hardness:
154 mg/L
Test temperature:
25 °C
pH:
8.1
Dissolved oxygen:
7.3 mg/L
Salinity:
92 mg/L
Duration:
7 d
Dose descriptor:
NOEC
Effect conc.:
3.64 mg/L
Nominal / measured:
meas. (initial)
Conc. based on:
test mat.
Basis for effect:
reproduction
Duration:
7 d
Dose descriptor:
LOEC
Effect conc.:
6.01 mg/L
Nominal / measured:
meas. (initial)
Conc. based on:
test mat.
Basis for effect:
reproduction
Validity criteria fulfilled:
yes
Conclusions:
The NOEC, LOEC, and chronic value for C. dubia, based on impairment of reproduction, were 3.64, 6.01 and 4.68 mg/L, respectively. RDX had no adverse effect on survival of C. dubia during the chronic study.

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