Registration Dossier

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

Additional information

For 1 -methyl piperazine, data are available for fish, daphnia and algae. An overview of all results is presented in the table below.The exposure concentrations were not quantified in the short term tests but in the semi-static long-term study with daphnia and in the algae study it was shown that the substance remains stable at least for 72 hours. It is therefore considered justified to also use the nominal test concentrations for those studies which were not supported with specific chemical analysis to quantify the exposure concentrations.


An overview of all results is presented in the table below: 



Daphnia magna

OECD 202, EC C.2

KEY Study

Safepharm Laboratories Ltd, UK

48h-EC50: >99 mg a.i./L

48h-NOEC:>99 mg a.i./L

Daphnia magna

OECD 211

KEY Study 

Dr.U.Noack-Laboratorien, 2013

21d-EC10 reprod: >99.9 mg a.i./L

21d-EC10 biomass: >99.9 mg a.i./L

Leuciscus idus

DIN 38412, part 15

KEY Study


BASF SE Department of Toxicology 1988

96h-LC50: >995 mg a.i./L (pH adjusted)


Desmodesmus subspicatus

OECD 201

KEY Study 

Dr.U.Noack-Laboratorien, 2013

72h-ErC50: >352 mg a.i./L

72h-ErC10: >352 mg a.i./L


Microorganisms, activated sludge

equivalent to OECD 209

Key Study 

BASF SE Department of Toxicology 1989

30m EC10 > 1000 mg/L