Registration Dossier
Registration Dossier
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EC number: 240-985-6 | CAS number: 16923-95-8
Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
Since dipotassium hexafluorozirconate rapidly dissociates into fluoride, potassium and zirconium ions upon dissolution in the environment, and only fluoride but not zirconium ions will remain in solution,it can be assumed that toxicity (if any) will be driven by the fluoride anion. Therefore, full read-across of chronic toxicity data for invertebrates of potassium fluoride (CAS #7789-23-3) and other fluorides based upon a molecular weight conversion is justified. The geometric mean of two NOEC values (3.7 mg F/L, 14.1 mg F/L) of 7.2 mg F/L derived in two reproductive studies of sodium fluoride with Daphnia magna results in a NOEC of 18.0 mg/l dipotassium hexafluorozirconate.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 18 mg/L
Additional information
Dipotassium hexafluorozirconate
Since dipotassium hexafluorozirconate rapidly dissociates into fluoride, potassium and zirconium ions upon dissolution in the environment, and only fluoride but not zirconium ions will remain in solution,it can be assumed that toxicity (if any) will be driven by the fluoride anion. Therefore, full read-across of chronic toxicity data for invertebrates of potassium fluoride (CAS #7789-23-3) and other fluorides based upon a molecular weight conversion is justified (see below).
Potassium fluoride
The EU RAR summarises the effects of two reproductive studies of sodium fluoride on Daphnia magna. The two studies report NOEC values of 3.7 and 14.1 mg F/L, with an arithmetic mean of 8.9 mg F/L. The ICD reports additional EC50 values in the range of 10 - 48 mg F/L.
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