Registration Dossier
Registration Dossier
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EC number: 205-864-4 | CAS number: 156-87-6
Additional toxicological data
Administrative data
- Endpoint:
- additional toxicological information
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
Data source
Reference
- Reference Type:
- publication
- Title:
- Cytotoxicity of Amino Alcohols to Rat Hepatoma-derived Fa32 Cells
- Author:
- Scheers EM, Forsby A, Dierickx PJ
- Year:
- 2 002
- Bibliographic source:
- ATLA 30: 309-312 ( Nineteenth Scandinavian Cell Toxicology Congress)
Materials and methods
- Type of study / information:
- Cytotoxicity of rat hepatoma-derived Fa32 cells
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- Cytotoxicity was measured by using a NRU (neutral red uptake) inhibition assay and was quantified by determination of the NI50, i.e. the concentration of test compound needed to induce a 50% reduction in NRU.
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 3-aminopropan-1-ol
- EC Number:
- 205-864-4
- Cas Number:
- 156-87-6
- Molecular formula:
- C3H9NO
- IUPAC Name:
- 3-aminopropan-1-ol
- Test material form:
- liquid
Constituent 1
Results and discussion
Any other information on results incl. tables
The NI50of 3-aminopropan-1 -ol was 13.4 ± 2.3 mM.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
