Registration Dossier

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Administrative data

Description of key information

The substance is present in the following carcinogen lists:

- European harmonized classification: Carc. 1B; H350 (CLP)

- NIOSH: http://www.cdc.gov/niosh/topics/cancer/npotocca.html#d

- IARC: Group 2B: "Possibly carcinogenic to humans"

- NTP's 11th Report on Carcinogens: Part B: "Reasonably Anticipated to be a Human Carcinogen"

Carcinogenic Potency Database, for the substance, enables to identify the target organs below, all by oral administration.

Key value for chemical safety assessment

Carcinogenicity: via oral route

Endpoint conclusion
Endpoint conclusion:
adverse effect observed
Organ:
kidney
liver
lungs
vascular system

Justification for classification or non-classification

The substance is subject of a harmonized classification as a carcinogen: Carc. 1B; H350 (CLP).

Additional information

The substance is a carcinogen in animals and a suspected carcinogen in humans. Further data can be found in IARC monograph and are not required at this tonnage level.

Carcinogenicity: via oral route (target organ): cardiovascular / hematological: other; digestive: cecum; digestive: liver; respiratory: lung; urogenital: kidneys