Registration Dossier
Registration Dossier
Diss Factsheets
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EC number: 201-248-4 | CAS number: 80-08-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
Under the conditions of a short term exposure to fish, the test of the 4,4’-DDS induced no lethal effects in carp at or below 100 mg/l (96h-LC0 = 100 mg/l).
For a long term toxicity evaluation on aquatic invertebrates, the test revealed that the 4,4’-DDS did not affect reproduction of Daphnia magna at 0.22 mg/l after 21 days of exposure (21 -day NOEC for reproduction = 0.22 mg/l). And a 21-day LOEC for reproduction of 0.46 mg/l was found. At the highest test concentration of 1.0 mg/l, this caused complete mortality of parental daphnids.
Under the conditions of the activated sludge respiration inhibition test, 4,4’-DDS was slightly toxic to waste water (activated sludge) bacteria. The EC50 was above the highest loading rate tested, a loading rate of 1000 mg/l (EC50 > 1000mg/l).
Based on the growth and reproduction toxicty test with freshwater algae, the EC50 is 2.7 mg/l (based on specific growth rate). The NOEC is 0.22 mg/l based on cell number.
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