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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Endpoint summary

Administrative data

Description of key information

Biodegradability in water

Ready biodegradability:


One study (Tecnologia America Latina, 2002), scored as reliability 2 according to Klimisch and selected as a key study, was performed according to ISO14593 (similar to OECD guideline 310). In this study, the biodegradation of 4-tert-butylpyrocatechol (4 -TBC) was followed during 28 days, at an initial concentration of 20 mg carbon/L (27.7 mg 4-TBC/L). Inoculum used in the test was an activated sludge at a concentration of 4 mg/L taking in an aeration basin of a sewage treatment plant of domestic effluents. After 28 days, the percentage of degradation was 24.7%based on CO2evolution. On the basis of this study, 4-tert-butylpyrocatechol is not readily biodegradable.

Inherent biodegradability:


One study in aerobic conditions (Harlan, 2010), scored as reliability 1 according to Klimisch, was selected as a key study. The inherent biodegradability of 4 -tert-butylpyrocatechol (4 -TBC) (initial concentration: 143 mg/L), was tested in a Zahn-Wellens test during 28 days according to OECD guideline 302B. Inoculum used in a study was 300 mg/L of a sludge from a wastewater treatment plant, adapted.

After 28 days, the corresponding percentage of biodegradation obtained was 91% of DOC removal. More that 70% degradation of 4 -TBC occurred within the first seven days of the test, including the lag-phase and the log-phase. The log-phase was lower than 3 days. Under the test conditions, 4 -TBC is considered as inherent ultimately biodegradable.

Additional information