Registration Dossier
Registration Dossier
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EC number: 404-310-0 | CAS number: 10591-85-2 PERKACIT TBZTD; PERKACIT TBZTD PDR; PERKACIT TBZTD PDR-D; TBZD
Solubility in organic solvents / fat solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- solubility in organic solvents / fat solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- April 22, 1988 to August 12, 1988
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Remarks:
- Guideline study performed in compliance with GLP, available as unpublished report, no restrictions, fully adequate for assessment.
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 116 (Fat Solubility of Solid and Liquid Substances)
- Qualifier:
- according to guideline
- Guideline:
- other: Directive 84/449/EEC, Annex V, A.7
- GLP compliance:
- yes
- Specific details on test material used for the study:
- - Name of test material (as cited in study report): Tetrabenzylthiuram disulfide
- Physical state: Solid
- Storage condition of test material: At room temperature in the dark
- Analytical purity: 98 %
- Lot/batch No.: RB82 + RB87 + RB88 + RB92 + RB69 - Key result
- Medium:
- standard fat
- Solubility:
- ca. 190 g/kg solvent
- Temp.:
- 37 °C
- Test substance stable:
- yes
- Details on results:
- - Information on chemical stability: No significant difference were observed between the HPLC chromatograms of the standards and the samples.
- Other: After a shaking period of 24 hours there were no significant differences between the over- and undersaturated solution. Therefore, the fat solubility of the substance was calculated as a mean value from the results of the 24 hours measurements.
Reference
Description of key information
The solubility of the substance in standard fat was determined to be 1.9 g/kg at a temperature of 37 °C.
Key value for chemical safety assessment
- Solubility in mg/100g standard fat:
- 190
- At the temperature of:
- 20 °C
Additional information
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