Registration Dossier

Diss Factsheets

Physical & Chemical properties

Endpoint summary

Administrative data

Description of key information

Sodium (S)-lactate as such is a solid organic salt, but due to its hygroscopic properties, it is only available and marketed as an aqueous solution. Therefore, the melting and boiling point of “pure” Sodium (S)-lactate are calculated using QSAR and are 174.03 °C and 436.7 °C, respectively. The ionic compound has a water solubility of 1086 g/L at 25 °C which is derived from read across from its racemic counterpart, Sodium lactate (chirality has no or only minor influence on this physical-chemical property). The corresponding partition coefficient octanol-water was determined in a study conducted according to OECD 107 with log Pow -1.52 at 20 °C. As pure Sodium (S)-lactate is not available, the relative density of the substance can only be indicated for highly concentrated (60 - 77.15 % w/w) aqueous solutions. The values range from 1.3131 for a 60 % w/w solution to 1.4085 for a 77.15 % w/w solution and are also derived from read across from the respective aqueous Sodium lactate solutions (chirality has no influence on this physical-chemical property). The QSAR estimate for vapour pressure indicates a negligible value of 5.8E-8 Pa for the pure substance. A calculation of the pKa value was not possible as no half-equivalence point could be determined with the titration method conducted according to OECD 112. The surface tension of the target substance is 71.8 mN/m at 20.0 °C as determined in a GLP study conducted according to OECD 115 and EU Method A.5. In addition, Sodium (S)-lactate has neither flammable, explosive nor oxidizing properties.

Additional information