Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Henry's Law constant

Currently viewing:

Administrative data

Link to relevant study record(s)

Henry's law constant
Type of information:
calculation (if not (Q)SAR)
Migrated phrase: estimated by calculation
Adequacy of study:
key study
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
accepted calculation method
Principles of method if other than guideline:
QSAR estimation with HENRYWIN v. 1.30
GLP compliance:
6.9 Pa m³/mol
25 °C
Executive summary:

The Henry Law Constant of 4,4-methylenedicyclohexyl diisocyanate is 6.9 Pa*m³/mol at a temperature of 25 °C estimated with HENRYWIN v. 1.30 on the basis of the bond contribution method (Currenta, 2009).

Description of key information

The calculation of the Henry’s Law Constant is not suitable due to the hydrolysing properties of 4,4’-methylenedicyclohexyl diisocyanate.  

However, for the later derivation of PNECsediment and PNECsoil (chapter 7.1, 7.2) a Henry’s Law Constant of 6.9 Pa*m³/mol at a temperature of 25 °C was calculated with HENRYWIN v. 1.30 on the basis of the bond contribution method (Currenta, 2009a).

Key value for chemical safety assessment

Henry's law constant (H) (in Pa m³/mol):
at the temperature of:
25 °C

Additional information