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Toxicological information

Exposure related observations in humans: other data

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Administrative data

Endpoint:
exposure-related observations in humans: other data
Adequacy of study:
other information
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Publications: Review articles related to inhalation toxicity of isocyanates, also 4,4'-methylenedicyclohexyl diisocyanate

Data source

Referenceopen allclose all

Reference Type:
review article or handbook
Title:
Occupational asthma and extrinsic alveolitis due to isocyanates: current status and perspectives
Author:
Vandenplas O
Year:
1993
Bibliographic source:
British Journal of Industrial Medicine 50, 213-228
Reference Type:
review article or handbook
Title:
Respiratory effects of inhaled isocyanates
Author:
Karol MH
Year:
1986
Bibliographic source:
Critical Reviews in Toxicology 16, 4, 349-379

Materials and methods

Test material

Constituent 1
Reference substance name:
Reference substance 001
Details on test material:
Isocyanates in general; also 4,4'-methylenedicyclohexyl diisocyanate

Results and discussion

Applicant's summary and conclusion