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Ecotoxicological information

Short-term toxicity to fish

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Description of key information

Conclusions are based on read-across from analogue substances of a known category. Acute toxicity to fish (LL50) for 2,2-bis[[(2-ethyl-1-oxohexyl)oxy]methyl]propane-1,3-diyl bis(2-ethylhexanoate)(EC# 230-743-8) is expected to be >100 mg/l, i.e. >> water solubility.

Key value for chemical safety assessment

LC50 for freshwater fish:
100 mg/L

Additional information

Read across to structural analogue. All members of this category of esters have a hydrophobic nature. Based on structural similarities of the substance of interest and the members of the category it was concluded that it was justified to applyread across for this endpoint.

 

96-Hour Acute Toxicity Study in Carp with HATCOL 3331.

A limit test was performed exposing seven carp to a filtered (ca. 5 μm) HATCOL 3331 solution prepared at a loading rate of 100 mg/l and to a blank-control. The total test period was 96 hours.

HATCOL 3331 induced no visible effects in carp at the concentration obtained in a filtered solution prepared at a loading rate of 100 mg/l, corresponding to an average exposure concentration approaching the solubility limit, i.e. 0.22-0.27 mg/l.

In conclusion: Due to the very low solubility of HATCOL 3331 in water, concentration levels that might be toxic for carp could not be reached. Therefore, the 96h-LC50 exceeded the maximum solubility of HATCOL 3331 in test medium.