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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

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Description of key information

The test substance is estimated to be stable at pH 4, 7 and 9 at 50°C with an half-life period longer than one year at 25 °C at pH 4, 7 and 9.

Key value for chemical safety assessment

Half-life for hydrolysis:
1 yr
at the temperature of:
25 °C

Additional information

Hydrolysis is a common degradation route in the environment, namely the reaction of a substance with water with a net exchange of the X group with an OH at the reaction centre such that RX + H2O → ROH + HX. Hydrolysis is often dependent upon pH as the reaction is commonly driven by hydrogen or hydroxide ions. Hydrolysis kinetics are usually determined experimentally and should be used to consider the test type and whether parent or degradation product should be tested.

For the substance, also confirmed by calculation with HYDROWIN 2.0, it can be estimated that hydrolysis does not occur because there is not hydrolysable groups in any of the structures.

Hydrolysable organic groups are in fact those groups that can react with water like Esters, Anhydrides, Amides, Carbammates, Nitriles, Cyanates, Epoxides, Halomethanes, Alkylhalides, Urea and none of these groups are present within the substance or their impurities.

A test was conducted according to internationally accepted testing guidelines and according to GLP on an analogous substance of the Stilbene Fluorescent Whitening Agents category, group 3, CAS 16470-24-9, for which a reliable Hydrolysis study has been reported. The two substances (2 -A and 1 -DSA) have similar functional groups being 3a-MSA a dihydroxyethylamino derivative, while 1 -DSA is a diethylamino derivative, even potentially less reactive, both substances have no hydrolysable groups in the chemical structure. Quantity and chemical identity of the impurities have no influence on the possibility of Read Across for this end point. For further details refer to the Category Justification Report attached to the section 13 of this dossier.