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Short-term toxicity to fish

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Description of key information

LC50 (96 h) Zebra fish > 100 mg/l

Key value for chemical safety assessment

LC50 for freshwater fish:
100 mg/L

Additional information

LC50 was tested on Oncorhynchus mykiss in a GLP study according to OECD 203 with no effect up to 100 mg/l. Four summaries are then available of tests performed on fish with LC50 > 1000 mg/l, but no method, timing and species are actually available, therefore the reference conservative value of LC50 > 100 mg/l of the key study has been taken as the reference value for risk assessment.

As supporting study, a test performed on the analogous dihydroxyethyl derivative tetrasulphonated sodium salt (CAS 16470-24-9) is presented. The acute toxicity for Zebra fish was evaluated in the 96 hours screening test, according to the OECD guideline 203. Two doses were administrated at 562 and 1000 mg/l with no effect.

Two fish acute toxicity tests are available (Ciba-Geigy, 1994 and 1998) on CAS 16090-02-1 pre-treated with light in order to obtain a high percentage of photodegraded products and verify their impact on aquatic toxicity. Both tests resulted in a LC50 > 100 mg/l, demonstrating that those degradation products are no more dangerous for the environment than the parent compounds.

In conclusion no fish acute toxicity is expected for CAS 41098-56-0 or its photooxidation products.