Registration Dossier
Registration Dossier
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EC number: 939-513-8 | CAS number: -
pH
Administrative data
- Endpoint:
- pH
- Type of information:
- migrated information: read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Study meets generally accepted scientific principles, acceptable for assessment as supporting data
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 012
- Report date:
- 2012
Materials and methods
- Principles of method if other than guideline:
- pH-measurements (10g/l) taken in the laboratory for solutions of pure test substance with increasing stoichometric amounts of the corresponding base (NaOH).
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Methoxyethylaminebis(methylenephosphonic acid)
- IUPAC Name:
- Methoxyethylaminebis(methylenephosphonic acid)
- Details on test material:
- - Name of test material (as cited in study report): Methoxyethylaminebis(methylenephosphonic acid)
- Molecular weight (if other than submission substance): 263.1 g/mol
- Analytical purity: 95.3%
- Lot/batch No.: A2979
- Expiration date of the lot/batch: December 2012
- Stability under test conditions: stable under storage conditions
- Storage condition of test material: in a closed containment at room temperature, protected from humidity and sunlight.
Constituent 1
Results and discussion
pH valueopen allclose all
- pH value:
- 2.8
- Temp.:
- 20 °C
- Concentration:
- 10 g/L
- Remarks on result:
- other: Stoichiometric loading of base equivalent to MeOEABMP
- pH value:
- 3.8
- Temp.:
- 20 °C
- Concentration:
- 10 g/L
- Remarks on result:
- other: Stoichiometric loading of base equivalent to MeOEABMP-1Na
- pH value:
- 5.5
- Temp.:
- 20 °C
- Concentration:
- 10 g/L
- Remarks on result:
- other: Stoichiometric loading of base equivalent to MeOEABMP-2Na
- pH value:
- 7.3
- Temp.:
- 20 °C
- Concentration:
- 10 g/L
- Remarks on result:
- other: Stoichiometric loading of base equivalent to MeOEABMP-3Na
- pH value:
- 11.1
- Temp.:
- 20 °C
- Concentration:
- 10 g/L
- Remarks on result:
- other: Stoichiometric loading of base equivalent to MeOEABMP-4Na
Any other information on results incl. tables
Table 1: Titration in water
Determination 1
Sample mass (mg) 82.82
Equivalent NaOH |
0 |
1 |
2 |
3 |
4 |
1N NaOH (ml) |
0.000 |
0.301 |
0.602 |
0.903 |
1.204 |
pH |
2.71 |
4.17 |
6.00 |
7.93 |
11.29 |
Determination 2
Sample mass (mg) 82.82
Equivalent NaOH |
0 |
1 |
2 |
3 |
4 |
1N NaOH (ml) |
0.000 |
0.301 |
0.602 |
0.903 |
1.204 |
pH |
2.69 |
3.91 |
5.87 |
7.89 |
11.27 |
Average |
2.70 |
4.04 |
5.94 |
7.91 |
11.28 |
Table 2: Titration in 0.2 M KCl
Determination 1
Sample mass (mg) 82.82
Equivalent NaOH |
0 |
1 |
2 |
3 |
4 |
1N NaOH (ml) |
0.000 |
0.301 |
0.602 |
0.903 |
1.204 |
pH |
2.77 |
3.78 |
5.49 |
7.29 |
11.09 |
Determination 2
Sample mass (mg) 82.82
Equivalent NaOH |
0 |
1 |
2 |
3 |
4 |
1N NaOH (ml) |
0.000 |
0.301 |
0.602 |
0.903 |
1.204 |
pH |
2.78 |
3.78 |
5.51 |
7.38 |
11.10 |
Average |
2.78 |
3.78 |
5.50 |
7.34 |
11.10 |
Applicant's summary and conclusion
- Conclusions:
- The pH has been determined using an acceptable scientific method. The result is considered reliable.
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