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Partition coefficient

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Reference
Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Test procedure in accordance with national standard methods (OECD) without GLP.
Qualifier:
according to guideline
Guideline:
OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
Deviations:
no
GLP compliance:
no
Remarks:
Not specified
Type of method:
HPLC method
Partition coefficient type:
octanol-water
Analytical method:
high-performance liquid chromatography
Key result
Type:
log Pow
Partition coefficient:
9.25
Temp.:
25 °C
Remarks on result:
other: pH not specified
Sample name Conc. of sample Solution (mg/ml) Retention time K log K log Pow % log Pow fraction log Pow
Weighted average
Peak 1 48.85 17.29 5.8 0.760 8.76 39.7 3.47 9.25
Peak 2 48.85 21.37 7.3 0.866 9.21 27.2 2.50
Peak 3 48.85 26.44 9.3 0.970 9.66 18.7 1.81
Peak 4 48.85 32.69 11.8 1.071 10.10 12.3 1.25
Peak 5 48.85 39.23 14.3 1.156 10.47 2.1 0.22
Conclusions:
log Pow of Hydrocarbons, C14-C17, n-alkanes, <2% aromatics: 9.25 at 25°C
Executive summary:

The log Pow of Hydrocarbons, C14-C17, n-alkanes, <2% aromatics was determined according to OECD 117.

The resulting equation was used to calculate the log Pow of the test substance: log Pow of Hydrocarbons, C14-C17, n-alkanes, <2% aromatics: 9.25 at 25°C.

Description of key information

The log Pow of Hydrocarbons, C14-C17, n-alkanes, <2% aromatics was determined according to OECD 117.

The resulting equation was used to calculate the log Pow of the test substance: log Pow of Hydrocarbons, C14-C17, n-alkanes, <2% aromatics: 9.25 at 25°C.

Key value for chemical safety assessment

Log Kow (Log Pow):
9.25
at the temperature of:
25 °C

Additional information