Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

Additional information

The test substance, 4,4'-Isopropylidenediphenol, oligomeric reaction products with 1-chloro-2,3-epoxypropane, reaction products with fatty acids, C18-unsatd., dimers, was accessed for its toxicity to fish, Daphnia and algae in GLP, O.E.C.D. test guideline studies. In the fish study the reported 96 hr LC50 was > 100 mg/L. The 48 hr EC50 value for Daphnia was also >100 mg/L (loading rate). An O.E.C.D. 201 72 hr algae study reported a nominal IC50 value of > 160 mg/L. Therefore, the test substance is not toxic to aquatic organisms. The EC50/LC50 value of 100 mg/L (loading rate) for two different aquatic species is the most appropriate value for derivation of aquatic PNECs.

The test substance, 4,4'-Isopropylidenediphenol, oligomeric reaction products with 1-chloro-2,3-epoxypropane, reaction products with fatty acids, C18-unsatd., dimers was reported to have an IC50 value of > 1000 mg/L for activated sewage sludge in an O.E.C.D. test guideline 209 study. Therefore, the test substance is not anticipated to have an adverse effect upon sewage sludge in waste-water treatment plants.