Registration Dossier
Registration Dossier
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EC number: 701-484-2 | CAS number: -
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (sensitising)
- Additional information:
The test substance indicated a positive response and had a calculated EC3 of 2% or 500 ug/cm2 in an O.E.C.D. test guideline 429 Local Lymph Node Assay. Therefore, the test substance, 4,4'-Isopropylidenediphenol, oligomeric reaction products with 1-chloro-2,3-epoxypropane, reaction products with fatty acids, C18-unsatd., dimers is considered to be a skin sensitizer.
Migrated from Short description of key information:
The test substance, 4,4'-Isopropylidenediphenol, oligomeric reaction products with 1-chloro-2,3-epoxypropane, reaction products with fatty acids, C18-unsatd., dimers was evaluated for skin sensitizing potential in an O.E.C.D. test guideline 429 Local Lymph Node Assay.
Respiratory sensitisation
Endpoint conclusion
- Additional information:
- Migrated from Short description of key information:
No data
Justification for classification or non-classification
Based on the outcome of an LLNA study demonstrating that the test substance, 4,4'-Isopropylidenediphenol, oligomeric reaction products with 1-chloro-2,3-epoxypropane, reaction products with fatty acids, C18-unsatd., dimers is a skin sensitiser, Classification as Category I, "May cause an allergic skin reaction" is appropriate.
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