Registration Dossier
Registration Dossier
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The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 209-218-2 | CAS number: 561-41-1
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- migrated information: read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
Data source
Referenceopen allclose all
- Reference Type:
- review article or handbook
- Title:
- RTECS Number: PC4180000
- Year:
- 2 012
- Bibliographic source:
- RTECS (Registry of Toxic Effects of Chemical Substances):- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 1,5,1951
- Reference Type:
- review article or handbook
- Title:
- DPIM: TJK000
- Author:
- Richard J. Lewis, Sr.
- Year:
- 2 007
- Bibliographic source:
- SAX (Sax's Handbook of Dangerous Industrial Materials):- Arzneimittel-Forschung. Drug Research. 1 (1951), 5.
- Reference Type:
- other: Authoritative data base
- Title:
- GCID: 251789
- Year:
- 2 011
- Bibliographic source:
- ACToR (Aggregated Computational Toxicology Resource):- Arzneimittel-Forschung. Drug Research. Vol. 1, Pg. 5, 1951.
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other:
- Principles of method if other than guideline:
- Data is from RTECS, SAX & Actor
- GLP compliance:
- not specified
- Test type:
- standard acute method
Test material
- Reference substance name:
- p,p',p''-tris(dimethylamino)trityl alcohol
- EC Number:
- 207-396-6
- EC Name:
- p,p',p''-tris(dimethylamino)trityl alcohol
- Cas Number:
- 467-63-0
- IUPAC Name:
- tris[4-(dimethylamino)phenyl]methanol
- Details on test material:
- - Name of test material : p,p',p''-tris(dimethylamino)trityl alcohol
- Substance type: Organic
- Molecular formula : C25H31N3O
- Molecular weight : 389.5331
Constituent 1
Test animals
- Species:
- mouse
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Route of administration:
- oral: unspecified
- Vehicle:
- not specified
- Control animals:
- not specified
Results and discussion
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- 1 000 other: mg/kg
- Based on:
- test mat.
- Remarks on result:
- other: Details of toxic effects not reported other than lethal dose value
Applicant's summary and conclusion
- Interpretation of results:
- Toxicity Category IV
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
- Conclusions:
- LD50 (Oral) for p,p',p''-tris(dimethylamino)trityl alcohol in Mouse is 1000 mg/kg suggests that the substance is toxic by the oral route.
- Executive summary:
LD50 (Oral) value of p,p',p''-tris(dimethylamino)trityl alcohol in Mouse is 1000 mg/kg suggests that the substance is toxic by the oral route.
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