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Water solubility

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Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
13-Jun-2012 to 16-Jun-2012
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
EU Method A.6 (Water Solubility)
GLP compliance:
not specified
Type of method:
column elution method
Water solubility:
< 0.05 mg/L
Temp.:
20 °C
Remarks on result:
other: pH value not provided

Results

 

Flow rate (ml/h)

Fraction No.

Stearyl Erucamide

pH value

25.0

1 (1-2)

< 0.05

6.4

 

2 (3-4)

< 0.05

6.3

 

3 (5-6)

< 0.05

6.3

 

4 (7-8)

< 0.05

6.3

 

5 (9-10)

< 0.05

6.3

 

6 (11-12)

< 0.05

6.2

 

7 (13-14)

< 0.05

6.3

 

8 (15-16)

< 0.05

6.3

 

 

 

 

12.5

1 (1-2)

< 0.05

6.0

 

2 (3-4)

< 0.05

6.1

 

3 (5-6)

< 0.05

6.2

 

4 (7-8)

< 0.05

6.2

 

5 (9-10)

< 0.05

6.1

 

6 (11-12)

< 0.05

6.1

 

7 (13-14)

< 0.05

6.1

 

8 (15-16)

< 0.05

6.2

 

 

Thus, the following value for water solubility of the test item Stearyl Erucamide can be reported according to test procedure according to EU test method L142A/57-66 (EEC A.6).

 

Water solubility Stearyl Erucamide < 0.05 mg/L

 

pH value HPLC water: 6.4

 

The water solubility was determined at 20 °C.

Working range

The calibration curve fits over the whole working range from 0.05 to 2.05 mg/L with r2= 1. A quadratic fit was used.

 

Recovery

In the course of the recovery experiment, an average recovery rate of 99 % was determined.

Conclusions:
Interpretation of results: insoluble (< 0.1 mg/L)

Description of key information

< 0.05 mg/L at 20 °C

Key value for chemical safety assessment

Water solubility:
0.05 mg/L
at the temperature of:
20 °C

Additional information

A water solubility value of < 0.05 mg/L at 20 °C was determined according to EU Method A.6 (column elution).