3,5,8-Trioxa-4-phosphaundec-10-en-1-aminium, 4-hydroxy-N,N,N,10-tetramethyl-9-oxo-, inner salt, 4-oxide

Vapour pressure

Administrative data

Endpoint:

vapour pressure

Type of information:

experimental study

Adequacy of study:

key study

Study period:

20 November 2008 to 19 March 2009

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

other: see 'Remark'

Remarks:

This study was conducted in accordance with relevant international Guideline (OECD 104) using a vapour pressure balance. The test report presented enough information to satisfy justification of the study fulfilling relevant validity criteria, and the description of methodology employed made the study wholly reproduceable.

Cross-reference

Cross-reference 1

Reason / purpose for cross-reference:

reference to same study

Cross-reference 2

Reason / purpose for cross-reference:

reference to other study

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2009

Report date:

2009

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

OECD Guideline 104 (Vapour Pressure Curve)

Deviations:

no

Principles of method if other than guideline:

N/A

GLP compliance:

yes (incl. QA statement)

Remarks:

UK GLP Regulation (1999)

Type of method:

effusion method: vapour pressure balance

Test material

Test material information

Constituent 1

Reference substance name:

-

EC Number:

417-560-0

EC Name:

-

Cas Number:

67881-98-5

Molecular formula:

C11H22NO6P

IUPAC Name:

trimethyl[2-({2-[(2-methylprop-2-enoyl)oxy]ethyl phosphonato}oxy)ethyl]azanium

Details on test material:

- Name of test material (as cited in study report): HEMA-PC (2-Methacryloyloxyethyl-2'-(trimethylammoniumethyl) phosphate
- Substance type: Pure Active Substance
- Physical state: Solid
- Analytical purity: 99 % (98-101 %)
- Impurities (identity and concentrations): 0.1 % by area (HPLC)
- Purity test date: 29 September 2008
- Lot/batch No.: SS148076
- Expiration date of the lot/batch: 27 October 2009 (lab default)
- Stability under test conditions: Stable
- Storage condition of test material: Under nitrogen at -20 degrees celsius in the dark.
- Other: N/A

Results and discussion

Vapour pressure

Temp.:

25 °C

Vapour pressure:

0 Pa

Any other information on results incl. tables

Table 1. Summary of Results for Replicate Runs

Run	Log10 [Vp(25^oC)]
1	-11.508
2	-11.509
3	-12.973
4	-12.830
5	-11.718
6	-12.141
Mean Vapour Pressure	-12.113 7.7E-13

Applicant's summary and conclusion

Conclusions:

Vapour pressure was determined successfully for HEMA-PC
Vapour Pressure = 7.77E-13 Pa at 25 degrees celsius

Executive summary:

Vapour pressure was determined successfully according to OECD Guideline 104.

Vapour Pressure = 7.77E-13 Pa at 25 degreed celsius.