Registration Dossier

Guidance on Safe Use

Guidance on Safe Use

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Administrative data

First-aid measures

Inhalation
Effects: May cause allergic respiratory reaction. Irritating to the respiratory system.
Symptoms: Shortness of breath, wheezing and coughing. The effect of inhalation may be delayed.
First Aid: Remove person to fresh air. If signs/symptoms continue, get medical attention. Show the safety data sheet to the doctor in attendance.

Skin contact
Effects: Irritating to skin.
Symptoms: Irritation with redness.
First Aid: Remove and wash contaminated clothing before re-use. Wash off immediately with plenty of water. If symptoms persist, call a doctor. Show the safety data to the doctor in attendance.

Eye contact
Effects: Irritation.
Symptoms: Irritation with redness.
First Aid: Hold eye open and rinse slowly and gently with water for 15-20 min. Remove contact lenses, if present, after the first five minutes, then continue rinsing the eye. If symptoms persist, call a doctor. Show the safety data sheet to the doctor in attendance.

Ingestion
Effects: Ingestion may cause gastrointestinal irritation, nausea, vomiting and diarrhea.
Symptoms: Irritation.
First Aid: Rinse mouth with water and drink plenty of water. If symptoms persist, call a doctor. Show the safety data sheet to the doctor in attendance.

Fire-fighting measures

Suitable extinguishing media: Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Unsuitable Extinguishing Media: none.
Hazardous combustion products: On burning, this material may generate toxig gases such as oxides of carbon, nitrogen and sulphur (COx, NOx and SOx).
Specific hazards arising from the chemical: May cause an allergic respiratory reaction.
Protective equipment and precautions for firefighters: Self-contained breathing apparatus.

Accidental release measures

Personal precautions
Wear suitable personal protection:
Respiratory Protection: In case of insufficient ventilation wear suitable respiratory equipment.
Eye protection: Safety glasses with side-shields.
Skin Protection: Long sleeved clothing.
Hand Protection: Protective gloves.

Environmental precautions: Prevent the material from entering surface water or sanitary sewer system. Do not discharge directly to a water source. If accidental spillage or washings enter drains or watercourses contact the local Environmental Authorities.

Methods for cleaning up: Avoid formation of dust and aerosols. Spilled preparation should be removed immediately to avoid formation of dust. Take up by mechanical means preferably by a vacuum cleaner equipped with a high efficiency filter. Flush remainder carefully with plenty of water. Avoid splashing and high pressure washing (avoid formation of aerosols). Ensure sufficient ventilation. Wash contaminated clothing.

Handling and storage

Handling:
Avoid formation of dust and aerosols. Ensure adequate ventilation

Storage:
Keep tightly closed in a dry and cool place.Temperature 0-25°C (32°F-77°F)
Storage conditions: In unbroken packaging - dry and protected from the sun.

Transport information

Land transport (ADR/RID)

UN number:
3077
Proper shipping name and description:
Environmentally hazardous substance, solid, n.o.s.
Chemical name:
Subtilisin
Language:
English
Class:
9
Classification code:
M7
Packaging group:
III
Labels:
9
Special Provisions:
274, 335, 375, 601

Inland waterway transport (ADN(R))

UN number:
3077
Shippingopen allclose all
Class:
9
Classification code:
M7
Packaging group:
III
Labels:
9
Remarksopen allclose all

Marine transport (IMDG)

UN number:
3077
Proper shipping name and description:
Environmentally hazardous substance, solid, n.o.s.
Chemical name:
Subtilisin
Class:
9
Packaging group:
III
EmS code:
F-A, S-F
Labels:
9
Marine pollutant
Remarksopen allclose all

Air transport ICAO/IATA

UN number:
3077
Proper shipping name and description:
Environmentally hazardous substance, solid, n.o.s.
Chemical name:
Subtilisin
Class:
9
Packaging group:
III
Labels:
9
Remarksopen allclose all
SpecialProvisionsopen allclose all

Exposure controls / personal protection

Respiratory Protection In case of insufficient ventilation wear an approved mask with a particle filter type P3 used according to the manufactures instruction.
Eye protection Safety glasses with side-shields
Skin Protection Long sleeved clothing.
Hand Protection Protective gloves of e.g. nitrile rubber or neoprene (thickness > 0.3 mm) according to EN 374-3. Expected breakthrough time: > 4 hours.

Stability and reactivity

Stable under recommended storage conditions

Disposal considerations

Dispose of in accordance with local regulations