Registration Dossier
Registration Dossier
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EC number: 239-898-6 | CAS number: 15793-73-4
Hydrolysis
Administrative data
Link to relevant study record(s)
- Endpoint:
- hydrolysis
- Data waiving:
- study technically not feasible
- Justification for data waiving:
- the study does not need to be conducted because the substance is highly insoluble in water
- Endpoint:
- hydrolysis
- Type of information:
- calculation (if not (Q)SAR)
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Justification for type of information:
- Episuite/Hydrowin program was used to calculate the half-lives of the substance. The program was developed by the US Environmental Prevention Agency's Office of Pollution Prevention Toxics and Syracuse Research Corporation. Informartion about the the program is publically available.
- Principles of method if other than guideline:
- HYDROWIN v2.00 from EPIsuite, copyright by US Environmental Protection Agency
- Preliminary study:
- Due to the Hydrowin data set it can be concluded that the substance is hydrolytically stable.
- Transformation products:
- not measured
- Key result
- Remarks on result:
- hydrolytically stable based on preliminary test
- Remarks:
- Result is based on calculation
- Conclusions:
- Due to the result based on the HYDROWIN v2.00, the substance can be as assessed as hydrolytically stable.
Referenceopen allclose all
Description of key information
The registration substance bears no functional groups which can be cleaved by hydrolysis, except a cyclic amide structure. For these groups a calculation with EPIWIN shows that hydrolytical cleavage is unlikely.
In addition a study can technically not be conducted as the registration substance is highly insoluble in water.
Key value for chemical safety assessment
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
