Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
dermal absorption
Type of information:
(Q)SAR
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Data from database.
Justification for type of information:
QSAR prediction: migrated from IUCLID 5.6

Data source

Reference
Reference Type:
secondary source
Title:
Unnamed
Year:
2010
Report date:
2010

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: REACH guidance on QSARs R.6, May/July 2008
Principles of method if other than guideline:
Danish (Q)SAR database report

Test material

Constituent 1
Chemical structure
Reference substance name:
Methyl laurate
EC Number:
203-911-3
EC Name:
Methyl laurate
Cas Number:
111-82-0
Molecular formula:
C13H26O2
IUPAC Name:
methyl dodecanoate
Details on test material:
- Name of test material (as cited in study report): methyl laurate
- Analytical purity: no data

Results and discussion

Absorption in different matrices:
Dermal absorption of methyl laurate was predicted to be 0.001 mg/cm²/event (low).

Applicant's summary and conclusion