Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
dermal absorption
Type of information:
(Q)SAR
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Data from database
Justification for type of information:
QSAR prediction: migrated from IUCLID 5.6

Data source

Reference
Reference Type:
secondary source
Title:
Unnamed
Year:
2010
Report date:
2010

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: REACH guidance on QSARs R.6, May/July 2008
Deviations:
no
Principles of method if other than guideline:
Danish (Q)SAR database report

Test material

Constituent 1
Chemical structure
Reference substance name:
Isopropyl laurate
EC Number:
233-560-1
EC Name:
Isopropyl laurate
Cas Number:
10233-13-3
Molecular formula:
C15H30O2
IUPAC Name:
isopropyl laurate
Details on test material:
- Name of test material (as cited in study report): isopropyl laurate
- Analytical purity: no data

Results and discussion

Absorption in different matrices:
Dermal absorption of isopropyl laurate was predicted to be 0.00047 mg/cm²/event (very low).

Applicant's summary and conclusion