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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Toxicity to birds

Currently viewing:

Administrative data

Endpoint:
short-term toxicity to birds: acute oral toxicity test
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
documentation insufficient for assessment

Data source

Referenceopen allclose all

Reference Type:
publication
Title:
The acute oral toxicity, repellency, and hazard potential of 998 chemicals to one or more species of wild and domestic birds
Author:
Schafer EW Jr, Bowles WA Jr, Hurlbut J
Year:
1983
Bibliographic source:
PMID: 6882015, Arch Environ Contam Toxicol. 12(3):355-82
Reference Type:
review article or handbook
Title:
Sodium azide
Author:
Lewis RJ
Bibliographic source:
Sax's Dangerous Properties of Industrial Materials, 9th ed. 1996, 2947-8
Reference Type:
other: method describing paper
Title:
Susbstituted Phenyl N-Methylcarbamates as Temporary Immobilizing Agents for Birds
Author:
Schafer, EW, Starr RI, Cunningham DJ, Decino TJ
Year:
1967
Bibliographic source:
J Agric Food Chem 15(2): 287-9

Materials and methods

Test guidelineopen allclose all
Qualifier:
equivalent or similar to guideline
Guideline:
OECD Guideline Draft (Avian Repellency Test) (not officially approved)
Qualifier:
equivalent or similar to guideline
Guideline:
EPA OPPTS 850.2100 (Avian Acute Oral Toxicity Test)
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
Sodium azide
EC Number:
247-852-1
EC Name:
Sodium azide
Cas Number:
26628-22-8
Molecular formula:
N3Na
IUPAC Name:
sodium azide
Dose method:
gavage
Analytical monitoring:
not specified
Vehicle:
yes

Test organisms

Test organisms (species):
other: Agelaius phoeniceus
Details on test organisms:
TEST ORGANISM
- Common name: red-winged blackbird
- Source: wild-trapped
- Age at test initiation (mean and range, SD): no data
- Weight at test initiation (mean and range, SD): no data
- Sexes used: no data
- Cultural background:
- Disease free: no data
- Kept according to standard practices: yes

Study design

Limit test:
no
Total exposure duration (if not single dose):
7 d
Remarks:
single treatment with 7d post-observation period
Post exposure observation period:
single treatment with 7d post-observation period
No. of animals per sex per dose and/or stage:
no data
Control animals:
not specified
Nominal and measured doses / concentrations:
no data
Details on test conditions:
ACCLIMATION
- Acclimation period: 2-6 weeks
- Acclimation conditions (same as test or not):same as test
- Feeding: ad libitum
- Health (any disease or mortality observed): not reported
- Fasting period before study: no data


FEED WITHHOLDING PERIOD BEFORE DOSING
- No. of days: no data


PEN SIZE AND CONSTRUCTION MATERIALS
- Description: no data
- Floor covering: no data
- Compliant to good husbandry practices: no
- Suitable to avoid crowding stress: yes
- Caging: individual


NO. OF BIRDS PER REPLICATE
- For negative control: no data
- For vehicle control: no data
- For treated: no data


NO. OF REPLICATES PER GROUP
- For negative control: no data
- For vehicle control: no data
- For treated: no data

Examinations

Details on examinations and observations:
Data recorded included affectation time, induction and duration of immobilization, mortality, regurgitation, weight gain or loss, and any unique physiological effects exhibited by the birds.

Results and discussion

Effect levels
Dose descriptor:
LD50
Effect level:
23.7 mg/kg bw
Basis for effect:
mortality
Repellency factors (if applicable):
R50 = 76.9 mg/kg

Applicant's summary and conclusion

Conclusions:
The LD50 (oral, red-winged blackbird) is 23.7 mg/kg.
Executive summary:

The acute oral toxicity, repellency, and hazard potential of 998 chemicals to one or more of 68 species of wild and domestic birds was determined by standardized testing procedures. Redwinged blackbirds were the most sensitive of the bird species tested on a large number of chemicals.


The LD50 (oral) for the toxicity of sodium azide to red-winged blackbird (Agelaius phoeniceus) was reported to be 23.7 mg/kg bw.