Registration Dossier
Registration Dossier
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EC number: 215-676-4 | CAS number: 1341-49-7
Endpoint summary
Administrative data
Description of key information
The acute oral LD50 of the substance in the rat is reported to be 130 mg/kg bw (Musch & Hoffer, 1990); no data are available for acute dermal or inhalation toxicity however waiver are appropriate for these endpoints due to the corrosive nature of the substance.
Key value for chemical safety assessment
Acute toxicity: via oral route
Endpoint conclusion
- Dose descriptor:
- LD50
- Value:
- 130 mg/kg bw
Additional information
The acute oral LD50 of the substance in the rat is reported to be 130 mg/kg bw (Musch & Hoffer, 1990). Ammonium hydrogendifluoride is listed on Annex I of Directive 67/548/EEC with classification as Corrosive (R34) 'Causes burns'. Testing for acute dermal and inhalation toxicity is not required and cannot be justified for reasons of animal welfare.
Justification for classification or non-classification
Ammonium hydrogendifluoride is listed on Annex I of Directive 67/548/EEC with classification as (R25) 'Toxic if swallowed'. This classification is consistent with the data availabel: no chnage to this classification is proposed.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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