Registration Dossier
Registration Dossier
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EC number: 910-757-7 | CAS number: -
Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
A GLP-study according to OECD guideline 202 Part 2 (Daphnia Reproduction Test) is available for the reaction mass of divinylbenzene and ethylstyrene. The 21-day NOEC (based on reproduction) for DVB-HP (80% divinylbenzene/20% ethylstyrene) was 0.353 mg/L in a chronic exposure with Daphnia magna.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 0.353 mg/L
Additional information
One high quality (Klimisch rating 1) chronic toxicity study with Daphnia magna was performed using DVB-HP (approximately 80% divinylbenzene and 20% ethylstyrene). The 21-day NOEC (based on reproduction) was 0.353 mg/L. The 21-day LOEC and EC50 (based on reproduction) were 0.711 mg/L and 0.718 mg/L, respectively. The 21-day LC50 was 1.06 mg/L. Since the toxicity of the reaction mass of divinylbenzene/ethystyrene increases with increasing divinylbenzene content (based on data from acute toxicity studies with Daphnia magna and freshwater fish), the NOEC for DVB-HP is expected to be a conservative estimate of toxicity for all other grades of the reaction mass of divinylbenzene and ethystyrene containing less than 80% divinylbenzene.
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