Registration Dossier
Registration Dossier
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EC number: 214-604-9 | CAS number: 1163-19-5
Short-term toxicity to fish
Administrative data
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Study was performed by Japan's Chemicals Inspection & Testing Institute, MITI, Tokyo. Cited in the 2002 EU RAR on DecaBDE.
Data source
Referenceopen allclose all
- Reference Type:
- publication
- Title:
- Biodegradation and Bioaccumulation Data of Existing Chemicals Based on the CSCL Japan
- Author:
- Anonymous
- Year:
- 1 992
- Bibliographic source:
- Eds. Chemical Inspection & Testing Insitute, Japan Chemical Industry Ecology-Toxicology & Information Center, Tokyo, Japan
- Reference Type:
- publication
- Title:
- Unnamed
- Year:
- 2 002
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: Japanese Industrial Standard JIS K 0102-1986-71 "Testing methods for industrial waste water"
- Deviations:
- no
- Principles of method if other than guideline:
- 48 h acute toxicity test in the orange-red killifish. performed as a preliminary to fish bioaccumulation study.
- GLP compliance:
- no
Test material
- Reference substance name:
- Bis(pentabromophenyl) ether
- EC Number:
- 214-604-9
- EC Name:
- Bis(pentabromophenyl) ether
- Cas Number:
- 1163-19-5
- Molecular formula:
- C12Br10O
- IUPAC Name:
- bis(pentabromophenyl) ether
Constituent 1
Sampling and analysis
- Analytical monitoring:
- no
Test solutions
- Vehicle:
- yes
Test organisms
- Test organisms (species):
- Oryzias latipes
Study design
- Test type:
- other: static or semi-static
- Water media type:
- freshwater
- Limit test:
- yes
- Total exposure duration:
- 48 h
- Post exposure observation period:
- no
Test conditions
- Hardness:
- Met Ministry of Health and Welfare (Au 31, 1978) ordinance for total hardness.
- Test temperature:
- 25 +- 2 degrees C
- pH:
- Met water quality criteria for fisheries (Shandanhozin Nihon Suisansigen Hogokyokai, March 1983)
- Dissolved oxygen:
- Met water quality criteria for fisheries (Shandanhozin Nihon Suisansigen Hogokyokai, March 1983)
- Salinity:
- freshwater derived from well at Kurume Research Laboratories, Kurume, Japan
- Nominal and measured concentrations:
- 500 mg/L
- Reference substance (positive control):
- no
Results and discussion
Effect concentrations
- Duration:
- 48 wk
- Dose descriptor:
- LC50
- Effect conc.:
- > 500 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- The 48 h LC50 for DecaBDE in the orange-red killifish was > 500 mg/L.
- Executive summary:
The 48 h LC50 for DecaBDE in the orange-red killifish was > 500 mg/L.
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