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EC number: 203-576-3 | CAS number: 108-38-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Endpoint summary
Administrative data
Description of key information
Additional information
On the basis of the similarity of the structure and environmental fate and behaviour of the xylene isomers, data from all the xylene isomers have been read across and used to determine their likely environmental fate.
GLP-compliant, guideline studies are available for xylene isomers showing that they are ready biodegradable and these are supported by QSAR estimates and additional studies showing high levels of biodegradation. Tsao et al. (1998) showed that 50% o- and p-xylene applied to soil were mineralised in 23 and 13 days, respectively, in a study following a method similar to OECD 304A. Atkinson (1985) indicates that the xylene isomers would degrade by indirect photolysis in air, with a half-life of approximately 1 day. The xylene isomers are not expected to undergo hydrolysis due to the lack of hydrolysable functional groups.
Xylenes are expected to have low potential for bioaccumulation based on a measured BCF of 29 in fish for mixed xylene isomers. The measured log Koc value of 2.73 for o-xylene indicates that xylene isomers are expected to have moderate adsorption to suspended solids and sediment in water.
The available data indicate that xylene isomers are readily biodegradable. Therefore, based on the screening criteria for persistence in the PBT assessment, the individual xylene isomers are not considered to be persistent (P) or very persistent (vP). The xylene isomers have a log Kow in the range of 3.12 to 3.2 and the measured BCF for mixed xylenes is 25.9 L/kg. Therefore, on the basis of the screening and definitive criteria, the xylene isomers are not considered bioaccumulative (B) or very bioaccumulative (vB).
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