Registration Dossier
Registration Dossier
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EC number: 205-743-6 | CAS number: 149-57-5
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
The substance is with high probability acutely not harmful to aquatic invertebrates.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Dose descriptor:
- EC50
- Effect concentration:
- 913 mg/L
Additional information
Data on the acute toxicity to aquatic invertebrates of 2-ethylhexanoic acid are available. However, as the acid induces a pH-shift in the test solutions, the acceptable pH-range according to OECD 202 is not met. The observed immobilization is partly due to pH effects and not due to the inherent toxicity of the substance.
Therefore, a study with the sodium salt of 2-ethylhexanoic acid (sodium 2-ethylhexanoate, CAS 19766-89-3) was used as key study. The salt does not cause a pH-shift in the test solutions and therefore resembles the acid after neutralization.
The study was conducted under supervision of the Japanese Ministry of the Environment. The study was performed according to OECD 202 under GLP with analytical monitoring. The test concentrations were analytically verified and deviated less than 20% from the nominal concentrations. After 48 hours an EC50 of 913 mg/L was estimated (nominal, analytically verified, NITE 2002, report no.: A010465-4).
Based on the valid result for sodium 2-ethylhexanoic acid, it can be concluded that the substance is with high probability acutely not harmful to aquatic invertebrates.
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