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Physical & Chemical properties

Melting point / freezing point

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The submission substance is a liquid at room temperature (20ºC), and according to first principles of chemistry, the addition of any substance to pure water will depress the freezing point of pure water to below 0ºC.  As such, it is scientifically reasonable to expect the melting point of the submission substance to be less than 0ºC.
However, according to Guidance on Information Requirements and Chemical Safety Assessment Chapter R.7a: Endpoint Specific Guidance, R.7.1.2, the melting point of a substance is environmentally relevant because it determines the temperature at which a substance changes its physical state from solid to liquid and thereby gives an indication of the distribution of the substance within and between the environmental media: water, soil and air. As the submission substance is extremely soluble in water (at least 901530 mg/L), and given its predicted melting point of less than 0ºC, it can reasonably be predicted that the substance will partition into the aquatic compartment. Thus, according to section 1 of REACh (Regulation (EC) No 1907/2006) Annex XI, the melting point study (required in Annex VII section 7.2) does not need to be conducted.

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