Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

Additional information

Acute toxicity studies have been conducted in fish, daphnia and algae. The EC50s/LC50s for propylene glycol phenyl ether is 280 mg/L for fish (Fathead minnow), 370mg/L for Daphnia and >100 mg/L in algae, while the algal NOEC was 55.5 mg/L. Since 42.7% inhibition of the growth rate was observed at the highest tested concentration of 100 mg/L, this concentration will be considered as a conservative estimation of the algal EC50, which indicates that alga was the most sensitive species tested. This value will therefore be used in the PNEC derivation. The EC50 determined in a respiration inhibition test according is greater than 1000 mg/L. Propylene glycol phenyl ether is readily biodegradable and has very low potential for bioaccumulation (log Kow <2). According to REACH Annex IX requirements, long-term toxicity testing shall only be considered when the chemical safety assessment indicates the need for further investigations. Hence, long-term testing in aquatic species (fish and invertebrate) can be waived.