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Toxicological information

Basic toxicokinetics

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Administrative data

Endpoint:
basic toxicokinetics, other
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study with acceptable restrictions

Data source

Reference
Reference Type:
other: ECHA Summary
Title:
Unnamed
Year:
1987

Materials and methods

Objective of study:
other: To examine the skin penetration of a 5 % (w/w) formulation of the test substance after a single application.
Test guideline
Qualifier:
according to guideline
Guideline:
other: Penetration through human epidermis in vitro.
GLP compliance:
yes

Test material

Constituent 1
Chemical structure
Reference substance name:
Tris(2-ethylhexyl)-4,4',4''-(1,3,5-triazine-2,4,6-triyltriimino)tribenzoate
EC Number:
402-070-1
EC Name:
Tris(2-ethylhexyl)-4,4',4''-(1,3,5-triazine-2,4,6-triyltriimino)tribenzoate
Cas Number:
88122-99-0
Molecular formula:
C48H66N6O6
IUPAC Name:
2-ethylhexyl 4-({4,6-bis[(4-{[(2-ethylhexyl)oxy]carbonyl}phenyl)amino]-1,3,5-triazin-2-yl}amino)benzoate
Radiolabelling:
no

Test animals

Species:
other: Proben menschlicher Epidermis

Administration / exposure

Route of administration:
dermal
Vehicle:
other: other: 5 % Prüfsubstanz in einer Sonnenschutzmittel-Formulierung «ENGLISCH+ 5 % test substance in a sun-screening product formulation.

Results and discussion

Applicant's summary and conclusion