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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
short-term toxicity to fish
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Guideline study with acceptable restrictions

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1989
Report date:
1989

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: German Industrial Standard DIN 38412 part 15
GLP compliance:
no

Test material

Constituent 1
Reference substance name:
DMHD solution
IUPAC Name:
DMHD solution
Details on test material:
- Name of test material (as cited in study report): DMHD
- Physical state: liquid
- Analytical purity: no data

Sampling and analysis

Analytical monitoring:
no

Test solutions

Vehicle:
no

Test organisms

Test organisms (species):
Leuciscus idus
Details on test organisms:
TEST ORGANISM
- Common name: golden orfe
- Source: Fischzucht Paul Eggers, Hohenwestedt, Germany
- Length at study initiation (length definition, mean, range and SD): 7.2 cm (6.2 - 7.9 cm)
- Weight at study initiation (mean and range, SD): 3.5 g (2.4 - 4.4 g)
- Feeding during test: none


ACCLIMATION
- Acclimation period: 3 months
- Acclimation conditions (same as test or not): yes
- Type and amount of food: grwoing feed F/B 50
- Health during acclimation (any mortality observed): no

Study design

Test type:
static
Water media type:
freshwater
Limit test:
no
Total exposure duration:
96 h

Test conditions

Details on test conditions:
TEST SYSTEM
- Test vessel:
- Type (delete if not applicable): open
- Material, size, headspace, fill volume: 10l all glass aquaria
- Aeration: slight
- No. of organisms per vessel: 10
- No. of vessels per concentration (replicates): 1
- No. of vessels per control (replicates): 1
- No. of vessels per vehicle control (replicates): none
- Biomass loading rate: 3.5 g fish/l


OTHER TEST CONDITIONS
- Adjustment of pH: no
- Photoperiod: 16:8

Reference substance (positive control):
yes
Remarks:
chloracetamid

Results and discussion

Effect concentrationsopen allclose all
Duration:
96 h
Dose descriptor:
LC50
Effect conc.:
4 600 - 10 000 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality (fish)
Duration:
96 h
Dose descriptor:
NOEC
Effect conc.:
2 150 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
behaviour

Applicant's summary and conclusion

Validity criteria fulfilled:
yes