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Partition coefficient

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Reference
Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2005-07-28 to 2005-12-07
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study with acceptable restrictions
Remarks:
Limited data on purity and stability, pH not reported
Qualifier:
according to guideline
Guideline:
OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
Deviations:
yes
Remarks:
No data on purity or stability of test substance; pH not reported.
Principles of method if other than guideline:
N/A
GLP compliance:
yes
Remarks:
Statement, no certificate
Type of method:
HPLC method
Partition coefficient type:
octanol-water
Specific details on test material used for the study:
- Name as cited in study report: Jeffamine D-230
- Substance type: Active
- Color: colorless
- Lot/Batch number: 4W512
- Test substance receipt: received 2005-07-05 727.9 g, received 2005-07-13 750.9 g
- Analytical Purity: 100%
Analytical method:
high-performance liquid chromatography
Key result
Type:
log Pow
Partition coefficient:
1.34
Temp.:
25 °C
Remarks on result:
other: pH not reported
Type:
Pow
Partition coefficient:
22.09
Temp.:
25 °C
Remarks on result:
other: pH not reported

Calculated log Pow for Reference Substances

- Thiourea - Not Applicable

- Trichloroethylene - 2.6

- Toluene - 2.79

- Napthalene - 3.27

- Phenanthrene - 4.47

- DDT - 6.27

Conclusions:
The partition coefficient (Pow) of the test substance was determined to be 22.09 with a log Pow of 1.34, by reverse phase HPLC estimation.

Description of key information

The partition coefficient (Pow) of the test substance was determined to be 22.09 with a log Pow of 1.34 at 25 °C by reverse phase HPLC estimation (Stillmeadow Inc., 2005).

Key value for chemical safety assessment

Log Kow (Log Pow):
1.34
at the temperature of:
25 °C

Additional information