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EC number: 227-231-1 | CAS number: 5726-19-2
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- December 26, 1997
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 C (Ready Biodegradability: Modified MITI Test (I))
- GLP compliance:
- not specified
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, non-adapted
- Details on inoculum:
- - Concentration of sludge: 30 mg/L
- Duration of test (contact time):
- 4 wk
- Initial conc.:
- 100 mg/L
- Based on:
- not specified
- Parameter followed for biodegradation estimation:
- other: BOD (Indirect analysis)
- Parameter followed for biodegradation estimation:
- test mat. analysis
- Remarks:
- (GC, direct analysis)
- Details on study design:
- Test equipment: Improved type for volatile substances.
- Key result
- Parameter:
- % degradation (test mat. analysis)
- Value:
- 100
- Sampling time:
- 4 wk
- Remarks on result:
- other: (GC, direct analysis)
- Details on results:
- The test substance was hydrolyzed in the test solution to form 2-methylcyclohexanol and acetic acid.
- Key result
- Parameter:
- BOD5
- Value:
- 99 other: Indirect analysis
- Validity criteria fulfilled:
- not specified
- Interpretation of results:
- readily biodegradable
- Conclusions:
- The test item 2-methylcyclohexyl acetate is determined to be readily biodegradable under test conditions.
- Executive summary:
The readily biodegradation test was performed by MITI according to OECD Guideline 301 C. A readily biodegradation test was performed on 2 -methylcyclohexyl acetate by MITI according to OECD Guideline 301 C. 30 mg/L of activated sludge were exposed to 100 mg/L test item for 4 weeks. The biodegradation obtained by indirect analysis was 99% (basis for effect: BOD), and by direct analysis 100% (basis for effect: GC). The test substance was hydrolyzed in the test solution to form 2 -methylcyclohexanol and acetic acid. The test substance 2 -methylcyclohexyl acetate was determined to be readily biodegradable.
- Endpoint:
- biodegradation in water: screening tests
- Type of information:
- (Q)SAR
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
- Remarks:
- Internationally accepted method, EPI-Suite, EPA (USA)
- Principles of method if other than guideline:
- Calculation by EPI-Suite, EPA (USA) / BIOWIN v4.10
- GLP compliance:
- no
- Details on results:
- The substances 2-methylcyclohexyl acetate was predicted to be readily biodegradable by EPI-Suite, EPA (USA) / BIOWIN v4.10.
- Validity criteria fulfilled:
- not applicable
- Interpretation of results:
- readily biodegradable
- Conclusions:
- The substances 2-methylcyclohexyl acetate was predicted to be readily biodegradable by EPI-Suite, EPA (USA) / BIOWIN v4.10 calculation method.
- Executive summary:
The substances 2-methylcyclohexyl acetate was predicted to be readily biodegradable by EPI-Suite, EPA (USA) / BIOWIN v4.10 calculation method.
Referenceopen allclose all
The substances 2-methylcyclohexyl acetate was predicted to be readily biodegradable by EPI-Suite, EPA (USA) / BIOWIN v4.10.
Description of key information
Key study: Test method OECD 301C. No data on GLP. The test item 2 -methylcyclohexyl acetate was determined to be readily biodegradable.
Supporting study: The experimental result was supported by calculation since, 2-methylcyclohexyl acetate was predicted to be readily biodegradable by EPI-Suite, EPA (USA) / BIOWIN v4.10.
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
Additional information
Key study: The readily biodegradation test was performed by MITI according to OECD Guideline 301 C. The biodegradation obtained by indirect analysis was 99% (basis for effect: BOD), and by direct analysis 100% (basis for effect: GC). Based on these results, the test item 2 -methylcyclohexyl acetate was determined to be readily biodegradable.
Supporting study: The experimental result was supported by calculation since, 2-methylcyclohexyl acetate was predicted to be readily biodegradable by EPI-Suite, EPA (USA) / BIOWIN v4.10.
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