Tetramethylammonium hydroxide

Oxidising properties

Link to relevant study record(s)

Reference

Endpoint:

oxidising solids

Data waiving:

study scientifically not necessary / other information available

Justification for data waiving:

the study does not need to be conducted because there are no chemical groups present in the molecule which are associated with oxidising properties and hence, the classification procedure does not need to be applied

Justification for type of information:

JUSTIFICATION FOR DATA WAIVING
An expert statement has been issued in which it was concluded that the substance has no oxidising properties.
-Expert statement: see included in study report (see Data Source)
-Expert: M.J.C. Brekelmans, MSc. (WIL Research Europe B.V., The Netherlands)


Expert statement
A test substance is considered an oxidizing substance when the burning time of a mixture of the substance and cellulose in a 4:1 or 1:1 sample-to-cellulose ratio (by mass) is less than or equal to the mean burning time of a 3:7 reference mixture (by mass) of potassium bromate and cellulose.
 
The test substance does not contain groups that act as an oxidizing agent. The oxygen atoms that are present in the molecular formula of the test substance are present in hydrate groups or hydroxide group. Based on this the test substance is considered to pose no function as oxidizing agent.
 
In conclusion, TMAH pentahydrate has no oxidizing properties.

Reason / purpose for cross-reference:

data waiving: supporting information

GLP compliance:

yes

Description of key information

From the evaluation of structural features of the substance, i.e. the absence of structural alerts, it was concluded in an expert statement (in accordance with EC A.17, UN TDG-MTC Appendix 6) that the UN classification procedure for oxidizing substances of Division 5.1 or the EC A.17 oxidising properties test does not need to be applied. The substance has no oxidizing properties. 
A statement rather than a full study was considered sufficient to cover this endpoint. The statement was written by an expert in accordance with EC A.17 and UN TDG-MTC Appendix 6  in compliance with the principles of GLP. 

Key value for chemical safety assessment

Oxidising properties:

no

Justification for classification or non-classification

Based on structural features, classification for the hazard 'oxidising solid' is not required according to CLP Regulation (EC) No. 1272/2008.