Registration Dossier

Diss Factsheets

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

Additional information


For TAED and DAED short-term aquatic ecotoxicity studies for all three trophic levels (fish, daphnia and algae) are available as well as studies on sludge respiration inhibition.


Fish:       OECD 203 LC50 (96h) > 500 mg/L

Daphnia: OECD 202 EC50 (48h) > 1000 mg/L

Algae:     OECD 201 ErC50 (72h) > 1000 mg/L, ErC10 (72h) 655 mg/L

Sludge:    OECD 209 EC50 ( 3h) > 1000 mg/L


Fish:       OECD 203 LC50 (96h) > 1000 mg/L

Daphnia: OECD 202 EC50 (48h) > 1000 mg/L

Algae:     OECD 201 ErC50 (72h) > 1000 mg/L, ErC10 (72h) > 1000 mg/L

Sludge:    OECD 209 EC50 (3h)   > 1000 mg/L

The short-term ecotoxicity data were used for the derivation of the PNEC aqua intermittent release (see Section 6 TAED DAED PNEC). As the TAED OECD 203 study has not shown any effects at the highest tested concentration (500 mg/L) for the PNEC aqua intermittent derivation 1000 mg/L was used.


TAED and DAED, Read across for DAED for 21d Daphnia

For reasons given in the waiving statements Section 6.1.2 no long-term fish toxicity tests were carried out. Instead a TAED long-term invertebrate study with daphnia was established. This 21d daphnia study with TAED was used for read across to DAED (see Section 6.1.4) for justification.


Daphnia:  OECD 211 NOEC (21d)     500 mg/L (most sensitive: adult mortality)

Algae:      OECD 201 ErC10 (72h)      655 mg/L

The algae ErC10 (72h) and the daphnia NOEC (21d) were used to derive the PNEC aqua for continous release (see Section 6 TAED DAED PNEC).