Registration Dossier
Registration Dossier
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EC number: 249-978-2 | CAS number: 29964-84-9
Endpoint summary
Administrative data
Description of key information
The acute toxicity of Isodecyl methacrylate was demonstrated to be low by the oral and dermal route. The absence of inhalation toxicity was demonstrated in a study where test animals were exposed to a saturated atmosphere. However, the inhalation route is not of relevance due to the low vapour pressure of the substance.
Key value for chemical safety assessment
Acute toxicity: via oral route
Endpoint conclusion
- Dose descriptor:
- LD50
- Value:
- 5 000 mg/kg bw
Acute toxicity: via dermal route
Endpoint conclusion
- Dose descriptor:
- LD50
- Value:
- 3 000 mg/kg bw
Additional information
The acute toxicity of Isodecyl methacrylate by the oral and dermal route was demonstrated to be low in animal tests with rats and rabbits. The results are confirmed by read-across to the structural closely related substances Ethylhexyl methacrylate (C8 Methacrylate ester) and Dodecyl methacrylate (C12 Methacrylate ester) The absence of inhalation toxicity was demonstrated in a study where test animals were exposed to a saturated atmosphere. However, the inhalation route is not of relevance due to the low vapour pressure of the substance.
Justification for classification or non-classification
According to the criteria as of directive 1272/2008/EC, no classification is warranted for the acute toxicity.
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