Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

Key value for chemical safety assessment

Skin sensitisation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not sensitising)
Additional information:

Ortho-toluene diamine, propoxylated was tested in the Guinea Pig Maximization Test (GPMT) on 15 female test animals (10 for the test item group, 5 control animals) for its skin sensitizing properties, according to the OECD Guideline 406. Concentrations of 5% (intradermal induction), 50% (topical induction and first challenge) and 25% (second challenge) of the test material in PEG 400 were used. Under the conditions of the test Ortho-toluene diamine, propoxylated was shown to exhibit no skin sensitization potential.

Migrated from Short description of key information:
Non-sensitiser using the guinea pig maximization test (GPMT), OECD 406

Justification for classification or non-classification

Results do not warrant classification.