Registration Dossier

Physical & Chemical properties

Flash point

Currently viewing:

Administrative data

Endpoint:
flash point of flammable liquids
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2018
Report date:
2018

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
EU Method A.9 (Flash-Point)
Qualifier:
according to guideline
Guideline:
ISO 3679 (Determination of flash point - Rapid equilibrium closed cup method)
Qualifier:
according to guideline
Guideline:
EPA OPPTS 830.6315 (Flammability)
GLP compliance:
yes (incl. QA statement)
Type of method:
closed cup
Flash point apparatus:
other: Rapid Tester NPV 310 of the company Normalab

Test material

Constituent 1
Reference substance name:
Valproic acid
IUPAC Name:
Valproic acid
Details on test material:
- Supplied by Parke-Davis Pharmaceutical Research Division
- The percentages of active component (valproic acid) were determined by a gas-chromatographic assay for purposes of dose calculation.

Results and discussion

Flash point
Key result
Flash point:
111 °C
Atm. press.:
1 013 hPa

Applicant's summary and conclusion

Interpretation of results:
GHS criteria not met
Conclusions:
Valproic acid has a flash point of 111.0°C (corrected and rounded down to the nearest multiple of 0.5°C) at 1013 hPa.