Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
pH
Type of information:
not specified
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Only secondary literature

Data source

Reference
Reference Type:
secondary source
Title:
Valproic Acid and Sodium Valproate: Comprehensive Profile
Author:
Ibrahim A. Alsarra, M. Al-Omar, and F. Belal
Year:
2005
Bibliographic source:
Profiles Of Drug Substances, Excipients, And Related Methodology volume 32

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
No data on method available

Test material

Constituent 1
Reference substance name:
Valproic acid
IUPAC Name:
Valproic acid
Constituent 2
Chemical structure
Reference substance name:
2-propylvaleric acid
EC Number:
202-777-3
EC Name:
2-propylvaleric acid
Cas Number:
99-66-1
Molecular formula:
C8H16O2
IUPAC Name:
2-propylpentanoic acid

Results and discussion

pH value
pH value:
>= 7 - <= 8

Applicant's summary and conclusion

Conclusions:
USP solution of valproic acid has a pH of 7-8